The Authors evaluate the issue about the search of first employment and the depressive effects possibly linked to it. The research includes two groups of unemployed and two control groups of workers. Sex difference has been taken into account. After a preliminary semi-structured interview, all subjects have been evaluated by the means of psychological tests. The psychometric values considered include the D and Ma scales of MMPI and their difference as proposed by Diamond, and the Beck Depression Rating Scale. The results do not show a significant correlation between the search for first employment and the presence of depressive traits.