The Body Image Quality of Life Inventory (BIQLI) was recently developed to quantify both the positive and negative effects of body image on one's psychosocial quality of life. The current study was conducted to further validate the measure with both men and women and to evaluate its psychometric reliability and validity among college students (N=603). Results confirmed that the 19-item measure was an internally consistent and unidimensional measure for both sexes. A significantly more favorable body image quality of life was reported by men than women, by African American than White women, and by women with lower body mass indices. Significant body image correlates included body image evaluation, investment, and situational dysphoria. A better body image quality of life was also related to higher self-esteem, optimism, and social support for both sexes and to less eating disturbance among women. The potential utility of this construct and unique instrument in further research, especially with medical populations, is discussed.