Exercise training and cardiovascular risk factors in type 1 diabetic adolescent girls

Pediatr Exerc Sci. 2007 Nov;19(4):408-19. doi: 10.1123/pes.19.4.408.


Sixteen postmenarcheal Type 1 diabetic adolescent girls were randomized into training (involving aerobic and strength exercises) and nontraining groups. Body composition (skinfold thickness), aerobic fitness (PWC170), plasma lipids, serum apolipoproteins, lipoprotein(a), leptin, and adiponectin were assessed before and after the 6-month period. After the 6-month period, fat mass and leptin increased significantly in the nontraining group but not in the training group. Conversely, in the latter group, fat-free mass increased (P < .01). Moreover, PWC170 improved and apolipoproteinB:apolipoproteinA-1 ratio decreased with physical training (P < .05). Thus, physical training reduces cardiovascular risks and the increase of insulin resistance risk factors in diabetic adolescent girls.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adiponectin / blood
  • Adolescent
  • Apolipoprotein A-I / blood
  • Apolipoproteins B / blood
  • Diabetes Mellitus, Type 1 / blood*
  • Diabetes Mellitus, Type 1 / physiopathology*
  • Female
  • Humans
  • Leptin / blood
  • Oxygen Consumption / physiology
  • Physical Education and Training*
  • Physical Fitness / physiology
  • Quality of Life
  • Risk
  • Skinfold Thickness


  • Adiponectin
  • Apolipoprotein A-I
  • Apolipoproteins B
  • Leptin