Stratus OCT in dominant optic atrophy: features differentiating it from glaucoma

J Glaucoma. 2007 Dec;16(8):655-8. doi: 10.1097/IJG.0b013e31804d23aa.


Purpose: To describe the Stratus optical coherence tomography (OCT) retinal nerve fiber layer (RNFL) thickness profile of dominant optic atrophy (DOA), to differentiate it from that of glaucoma.

Methods: RNFL thickness was measured using Stratus OCT in 32 eyes of 16 DOA patients.

Results: The temporal-most clock hour measurement was outside the 95% normal limit in 29 of the 32 DOA eyes (90.6%). The pattern of RNFL damage was bilaterally symmetrical in location and severity in all subjects.

Conclusion: Stratus OCT shows characteristic findings differentiating DOA from glaucoma.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Diagnosis, Differential
  • Female
  • Glaucoma / diagnosis*
  • Humans
  • Male
  • Nerve Fibers / pathology
  • Optic Atrophy, Autosomal Dominant / diagnosis*
  • Retina / pathology
  • Severity of Illness Index
  • Tomography, Optical Coherence / methods*