Improved naming after transcranial direct current stimulation in aphasia

J Neurol Neurosurg Psychiatry. 2008 Apr;79(4):451-3. doi: 10.1136/jnnp.2007.135277. Epub 2007 Dec 20.


Transcranial direct current stimulation (tDCS) has been proposed as an adjuvant technique to improve functional recovery after ischaemic stroke. This study evaluated the effect of tDCS over the left frontotemporal areas in eight chronic non-fluent post-stroke aphasic patients. The protocol consisted of the assessment of picture naming (accuracy and response time) before and immediately after anodal or cathodal tDCS (2 mA, 10 minutes) and sham stimulation. Whereas anodal tDCS and sham tDCS failed to induce any changes, cathodal tDCS significantly improved the accuracy of the picture naming task by a mean of 33.6% (SEM 13.8%).

MeSH terms

  • Aged
  • Anomia / physiopathology
  • Anomia / therapy*
  • Aphasia, Broca / physiopathology
  • Aphasia, Broca / therapy*
  • Cerebral Infarction / complications*
  • Cerebral Infarction / physiopathology
  • Electric Stimulation Therapy / methods*
  • Female
  • Frontal Lobe / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Occipital Lobe / physiopathology*
  • Pattern Recognition, Visual / physiology
  • Reaction Time / physiology
  • Semantics
  • Speech Production Measurement
  • Temporal Lobe / physiopathology*
  • Treatment Outcome