The appropriate length of great saphenous vein stripping should be based on the extent of reflux and not on the intent to avoid saphenous nerve injury

J Vasc Surg. 2007 Dec;46(6):1234-41. doi: 10.1016/j.jvs.2007.07.055.


Objective: To investigate the effect of stripping the below knee great saphenous vein (GSV) segment on varicose vein recurrence as well as any disability induced after saphenous nerve injury (SNI) during a 5-year period.

Methods: One hundred and six limbs (86 patients, 64 female, mean age 46 years), that underwent GSV stripping, to the knee or ankle level, were prospectively followed up at 1 month and 5 years postoperatively with clinical examination and color duplex imaging (CDI), in order to evaluate SNI and the development of recurrence. The extent of GSV stripping complied with preoperative CDI in 84 limbs (79%) that were subjected to GSV stripping to the ankle and full abolishment of duplex-confirmed reflux. Furthermore, 19 limbs (18%) underwent stripping restricted to the below knee level since the distal GSV was competent. On the contrary, in three limbs (3%), the extent of stripping did not comply with preoperative CDI due to the absence of varicosities in the tibia, and stripping was restricted to the knee level, although they had reflux along the whole GSV length.

Results: Overall recurrence was found in 24 out of 106 operated limbs (23%) after 5 years. Recurrence was found to be 20% (17/84) in the limbs with total GSV stripping and 32% (7/22) in the limbs with restricted GSV stripping (P > .05). However, the recurrence rate in the tibial area was significantly lower in limbs subjected to GSV stripping, which was in compliance with the preoperative CDI (9/103, 9%) compared with those that had undergone GSV stripping that was not in agreement with the preoperative CDI (3/3, 100%; P < .005). Neurological examination at 1 month postoperatively, revealed SNI in 17 limbs (16%). However, at the 5-year neurological reassessment, we found that seven out of these limbs (40%) were alleviated from SNI adverse symptoms presenting only deficits in sensation. In addition, no significance was found concerning SNI between limbs subjected to total and restricted GSV stripping (16/84 vs 1/22; P > .05).

Conclusions: Though SNI may occur after both restricted and total GSV stripping, this does not influence limb disability since any related symptoms seem to regress in almost half of the limbs 5 years postoperatively. Additionally, it seems that recurrence could be reduced in the tibial area if the level of GSV stripping complies with the extent of the ultrosonographically proven GSV reflux. Therefore, the extent of GSV stripping should not be guided by the intent of avoiding SNI.

Publication types

  • Clinical Trial
  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Disability Evaluation
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neurologic Examination
  • Patient Selection
  • Peripheral Nervous System Diseases / etiology*
  • Peripheral Nervous System Diseases / physiopathology
  • Prospective Studies
  • Recovery of Function
  • Saphenous Vein / diagnostic imaging
  • Saphenous Vein / innervation
  • Saphenous Vein / surgery*
  • Secondary Prevention
  • Severity of Illness Index
  • Time Factors
  • Treatment Outcome
  • Ultrasonography, Doppler, Color
  • Varicose Veins / diagnostic imaging
  • Varicose Veins / etiology
  • Varicose Veins / physiopathology
  • Varicose Veins / surgery*
  • Vascular Surgical Procedures / adverse effects*
  • Vascular Surgical Procedures / methods
  • Venous Insufficiency / complications*
  • Venous Insufficiency / diagnostic imaging
  • Venous Insufficiency / physiopathology
  • Venous Insufficiency / surgery