Pregnancy outcomes after uterine artery occlusion: prospective multicentric study

Fertil Steril. 2008 Nov;90(5):1886-91. doi: 10.1016/j.fertnstert.2007.08.033. Epub 2007 Dec 26.


Objective: To assess the reproductive outcomes after laparoscopic uterine artery occlusion (LUAO) and uterine artery embolization (UAE) in women with symptomatic fibroids.

Design: Prospective, clinical multicentric study.

Setting: Endoscopic center in the department of obstetrics and gynecology at a hospital in the Czech Republic.

Patient(s): Thirty-eight pregnant women after LUAO and 20 pregnant women after UAE.

Intervention(s): Laparoscopic uterine artery occlusion and UAE.

Main outcome measure(s): Pregnancy, abortion, preterm delivery, and live-birth rates.

Result(s): Pregnancies after uterine embolization had a statistically significantly higher rate for spontaneous abortion (56%) than did pregnancies after surgical uterine artery occlusion (10.5%). The risk of malpresentation (20%) and the rate for cesarean section (80%) after UAE similarly were higher than was the risk after laparoscopic occlusion; however, these differences were not statistically significant. Also, there were no significant differences between the groups in preterm deliveries (15.3% in the LUAO group vs. 20% in the UAE group).

Conclusion(s): Pregnancies of women who were treated with uterine embolization were at significantly increased risk for spontaneous abortion when compared with pregnancies of women treated with LUAO.

Publication types

  • Comparative Study
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortion, Spontaneous / etiology
  • Adult
  • Arteries / surgery
  • Cesarean Section
  • Czech Republic
  • Female
  • Humans
  • Labor Presentation
  • Laparoscopy / adverse effects*
  • Leiomyoma / surgery
  • Leiomyoma / therapy*
  • Live Birth
  • Pregnancy
  • Pregnancy Rate
  • Premature Birth / etiology
  • Prospective Studies
  • Risk Assessment
  • Uterine Artery Embolization / adverse effects*
  • Uterine Neoplasms / surgery
  • Uterine Neoplasms / therapy*
  • Uterus / blood supply*
  • Vascular Surgical Procedures / adverse effects*