Temporal properties of spatial channel of processing in hemianopia

Neuropsychologia. 2008 Feb 12;46(3):879-85. doi: 10.1016/j.neuropsychologia.2007.11.008. Epub 2007 Nov 19.

Abstract

The term blindsight, coined by Larry Weiskrantz, describes those discrimination abilities that can be elicited with visual stimuli restricted to the blindfield of a patient with occipital brain lesion or damaged optic radiation. Over the past 3 decades, many aspects of blindsight have been investigated including detection of basic stimulus attributes such as structure, colour and movement as well as more complex tasks such as discrimination of facial expressions and semantic processing. The neuronal mechanisms mediating blindsight rely on processing in subcortical and/or extrastriate areas. It appears that following the occipital brain damage, there is a restricted "window of processing" and stimulus parameters mainly outside this window may not lead to blindsight performance. Here we report how the restricted "window of processing" appears to have a specific spatio-temporal response profile, mainly tuned to low spatial frequencies and intermediate temporal frequencies. In addition, in a group of blindsight patients, we demonstrate that above chance detection performance is related to the target size. The findings have implications both for the reported incidence of blindsight and development of rehabilitation strategies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Brain Mapping*
  • Choice Behavior / physiology
  • Discrimination, Psychological / physiology*
  • Female
  • Hemianopsia / etiology
  • Hemianopsia / pathology*
  • Hemianopsia / physiopathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Photic Stimulation / methods
  • Psychophysics
  • Space Perception / physiology*
  • Visual Cortex / physiopathology*
  • Visual Fields / physiology*
  • Visual Pathways / pathology
  • Visual Pathways / physiopathology