Successful heart transplantation following neonatal necrotic enterovirus myocarditis

Pediatr Cardiol. 2008 Jul;29(4):834-7. doi: 10.1007/s00246-007-9182-z. Epub 2007 Dec 25.


Enterovirus myocarditis is a potentially devastating diagnosis in the neonatal setting, with an associated high mortality and risk for chronically impaired cardiac function. Transplantation may be a possible therapeutic option, but, due to the comparative scarcity of the presentation, the limited donor pool, and fears of viral persistence and recurrence of myocarditis (especially in the immunocompromised, post-transplant setting), there are no reported cases in the literature. This case report illustrates an encouraging one-year outcome following heart transplantation for necrotic enterovirus myocarditis in a neonate.

MeSH terms

  • Enterovirus Infections / complications*
  • Enterovirus*
  • Female
  • Heart Transplantation*
  • Humans
  • Infant, Newborn
  • Myocarditis / surgery*
  • Myocarditis / virology
  • Ventricular Dysfunction, Left / virology*