Histological analysis of microbleed after surgical resection in a patient with moyamoya disease

Neurol Med Chir (Tokyo). 2007 Dec;47(12):564-7. doi: 10.2176/nmc.47.564.


A 65-year-old male with moyamoya disease underwent surgical resection of a microbleed simultaneously with revascularization surgery. Histological examination identified several fragile arteries surrounding the microbleed. Microbleeds detected by T2*-weighted magnetic resonance imaging are considered to be a general marker of vascular vulnerability in cerebral angiopathy with a tendency to bleeding. The microbleeds observed in patients with moyamoya disease probably originate in bleeding from the fragile arteries.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Humans
  • Intracranial Hemorrhages / pathology*
  • Intracranial Hemorrhages / surgery*
  • Male
  • Microcirculation
  • Moyamoya Disease / complications*
  • Moyamoya Disease / surgery