A PMA degrading constitutive organomercurial lyase in a broad-spectrum mercury resistant Bacillus pasteurii strain DR2

Indian J Exp Biol. 1991 Dec;29(12):1147-9.


A broad-spectrum Hg-resistant strain of B. pasteurii DR2 utilized phenylmercuric acetate (PMA) as sole source of carbon. This bacterial strain contained a constitutive organomercurial lyase which specifically degraded PMA but not other organo-mercurials. This PMA-lyase activity was also stimulated to different extents when this bacterial strain was grown in presence of different organic compounds as sole source of carbon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacillus / drug effects
  • Bacillus / enzymology*
  • Drug Resistance, Microbial
  • Lyases / metabolism*
  • Mercury / pharmacology*
  • Phenylmercuric Acetate / metabolism*


  • Lyases
  • alkylmercury lyase
  • Mercury
  • Phenylmercuric Acetate