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. 2008 Jan;93(1):147-8.
doi: 10.3324/haematol.11771.

High-dose Chemotherapy and Autologous Stem-Cell Transplantation Without Consolidating Radiotherapy as First-Line Treatment for Primary Lymphoma of the Central Nervous System

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High-dose Chemotherapy and Autologous Stem-Cell Transplantation Without Consolidating Radiotherapy as First-Line Treatment for Primary Lymphoma of the Central Nervous System

Gerald Illerhaus et al. Haematologica. .
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Abstract

Thirteen patients (age 38-67 years) with primary lymphoma of the central nervous system (CNS) were treated with methotrexate and cytarabine/thiotepa induction-chemotherapy followed by high-dose carmustine/thiotepa and autologous stem-cell transplantation. Radiotherapy was restricted to patients who did not respond completely to chemotherapy. With a median follow up of 25 months, 3-year DFS and OS was 77%.

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