Modified constraint-induced therapy in chronic stroke: results of a single-blinded randomized controlled trial

Phys Ther. 2008 Mar;88(3):333-40. doi: 10.2522/ptj.20060029. Epub 2008 Jan 3.


Background and purpose: This single-blinded randomized controlled trial compared the efficacy of a reimbursable, outpatient, modified constraint-induced therapy (mCIT) protocol (half-hour therapy sessions occurring 3 days per week in which subjects used the more affected arm combined with less affected arm restriction 5 days per week for 5 hours; both of these regimens were administered during a 10-week period) with that of a time-matched exercise program for the more affected arm or a no-treatment control regimen.

Subjects: Thirty-five subjects with chronic stroke participated in the study.

Methods: The Action Research Arm Test (ARAT), Fugl-Meyer Assessment of Motor Recovery After Stroke (FM), and Motor Activity Log (MAL) were administered to the subjects.

Results: After intervention, significant differences were observed on the ARAT and MAL Amount of Use and Quality of Movement scales, all in favor of the mCIT group.

Discussion and conclusion: The data affirm previous findings suggesting that this reimbursable, outpatient protocol increases more affected arm use and function. Magnitude of changes was consistent with those reported in more intense protocols, such as constraint-induced therapy.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Disability Evaluation
  • Exercise Therapy / methods*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Restraint, Physical / physiology*
  • Single-Blind Method
  • Stroke / physiopathology
  • Stroke Rehabilitation*
  • Treatment Outcome
  • Upper Extremity / physiopathology*