Historical perspective of living donor liver transplantation

World J Gastroenterol. 2008 Jan 7;14(1):15-21. doi: 10.3748/wjg.14.15.


Living donor liver transplantation (LDLT) has gone through its formative years and established as a legitimate treatment when a deceased donor liver graft is not timely or simply not available at all. Nevertheless, LDLT is characterized by its technical complexity and ethical controversy. These are the consequences of a single organ having to serve two subjects, the donor and the recipient, instantaneously. The transplant community has a common ground on assuring donor safety while achieving predictable recipient success. With this background, a reflection of the development of LDLT may be appropriate to direct future research and patient-care efforts on this life-saving treatment alternative.

Publication types

  • Historical Article

MeSH terms

  • History, 20th Century
  • History, 21st Century
  • Humans
  • Liver Transplantation / history*
  • Living Donors / history*