Transcription: a mechanism for short-term memory

Curr Biol. 2008 Jan 8;18(1):R25-7. doi: 10.1016/j.cub.2007.11.017.


Yeast growing for a considerable time in glucose 'remember' a previous exposure to galactose, the inducer of its galactose-utilization (GAL) genes. This memory is conveyed by a cytoplasmically transmitted galactokinase working as a signal transducer.

Publication types

  • Comment

MeSH terms

  • Epigenesis, Genetic*
  • Galactose / metabolism
  • Gene Expression Regulation / physiology
  • Glucose / metabolism
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / metabolism
  • Signal Transduction
  • Transcription, Genetic / physiology*


  • Glucose
  • Galactose