Regulation of probiotic substances as ingredients in foods: premarket approval or "generally recognized as safe" notification

Antonia Mattia; Robert Merker

doi:10.1086/523329

Regulation of probiotic substances as ingredients in foods: premarket approval or "generally recognized as safe" notification

Clin Infect Dis. 2008 Feb 1:46 Suppl 2:S115-8; discussion S144-51. doi: 10.1086/523329.

Authors

Antonia Mattia¹, Robert Merker

Affiliation

¹ Division of Biotechnology and GRAS Notice Review, Office of Food Additive Safety, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, College Park, Maryland 20740, USA. antonia.mattia@fda.hhs.gov

PMID: 18181714
DOI: 10.1086/523329

Abstract

This article discusses options and examples of regulations or "generally recognized as safe" determinations that are related to microorganisms in food. A balanced picture of information about the microorganism and its characteristics is needed to make conclusions about its safety.

MeSH terms

Consumer Product Safety / legislation & jurisprudence*
Consumer Product Safety / standards
Food Industry / legislation & jurisprudence
Food Industry / standards*
Food Microbiology / legislation & jurisprudence*
Food Microbiology / standards
Food, Organic / standards*
Humans
Legislation, Drug
Legislation, Food*
Probiotics / standards*
Probiotics / therapeutic use
United States
United States Food and Drug Administration / legislation & jurisprudence