doi: 10.1016/j.jep.2007.11.037.
Epub 2007 Dec 4.
Antimicrobial potential of Glycyrrhiza glabra roots
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- PMID: 18182260
- DOI: 10.1016/j.jep.2007.11.037
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Antimicrobial potential of Glycyrrhiza glabra roots
J Ethnopharmacol.
.
Abstract
The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 microg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H(37)Ra and H(37)Rv strains at 29.16 microg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.
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