Tracking and prediction of arterial blood pressure from childhood to young adulthood in 868 patients with type 1 diabetes: a multicenter longitudinal survey in Germany and Austria

Diabetes Care. 2008 Apr;31(4):726-7. doi: 10.2337/dc07-1392. Epub 2008 Jan 9.

Abstract

Objective: Arterial blood pressure was followed in 868 patients with type 1 diabetes aged 6.0-19.9 years in 95 centers in Germany and Austria.

Research design and methods: European blood pressure reference data for 28,043 children and adolescents were used with respect to age and sex. Data were stratified into three groups: prepubertal, pubertal, and postpubertal.

Results: Up to 4% of the participants in the younger age-groups and 13.9% of the postpubertal patients exhibited blood pressure values >97th centile. Blood pressure levels correlated with A1C level and BMI Z score. Tracking of blood pressure revealed that children with elevated blood pressure had higher blood pressure in adolescence and young adulthood.

Conclusions: Patients with higher blood pressure in childhood showed elevated blood pressure later in life. We need to focus on the diagnosis of hypertension in children with type 1 diabetes and to study the efficacy of early intervention.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Austria / epidemiology
  • Blood Pressure / physiology*
  • Cardiovascular Diseases / epidemiology
  • Child
  • Diabetes Mellitus, Type 1 / physiopathology*
  • Diabetic Angiopathies / epidemiology*
  • Diastole
  • Female
  • Follow-Up Studies
  • Germany / epidemiology
  • Health Surveys
  • Humans
  • Hypertension / epidemiology
  • Longitudinal Studies
  • Male
  • Predictive Value of Tests
  • Systole