Prevalence and characteristics of left ventricular noncompaction in a community hospital cohort of patients with systolic dysfunction

Echocardiography. 2008 Jan;25(1):8-12. doi: 10.1111/j.1540-8175.2007.00560.x.


Background: Left ventricular noncompaction (LVNC) is felt to be a rare form of cardiomyopathy, although its prevalence in a nonreferred population is unknown. We examined the prevalence and clinical characteristics of LVNC in a community hospital cohort of adult patients with echocardiographic evidence of left ventricular (LV) systolic dysfunction.

Methods: All adult echocardiograms with global LV dysfunction and an LVEF < or = 45% over a 1-year period were reviewed for signs of LV noncompaction. Its presence was confirmed by the consensus of at least 2/3 readers specifically searching for this using standard criteria for noncompaction.

Results: A 3.7% prevalence of definite or probable LVNC was found in those with LVEF < or = 45% and a 0.26% prevalence for all patients referred for echocardiography during this period. This is appreciably higher than prior reports from tertiary centers.

Conclusion: Noncompaction may not be a rare phenomenon and is comparable to other more widely recognized but less common causes of heart failure such as peripartum myopathy, connective tissue diseases, chronic substance abuse and HIV disease.

MeSH terms

  • Analysis of Variance
  • Cardiomyopathies / diagnostic imaging*
  • Cardiomyopathies / epidemiology*
  • Chi-Square Distribution
  • Cohort Studies
  • Female
  • Hospitals, Community
  • Humans
  • Male
  • Ohio / epidemiology
  • Prevalence
  • Systole
  • Ultrasonography
  • Ventricular Dysfunction, Left / diagnostic imaging*
  • Ventricular Dysfunction, Left / epidemiology*