10-year case review of nutritional rickets in Children's Hospital of Michigan

Clin Pediatr (Phila). 2008 May;47(4):379-84. doi: 10.1177/0009922807311397. Epub 2008 Jan 11.

Abstract

Nutritional rickets has been on the rise in the United States. A chart review of patients with nutritional rickets from April 1995 to May 2005 was performed. Fifty-eight subjects were studied (62% males, 38% females, with an age range between 2 and 132 months). Of the subjects, 81% were African Americans and 14% were Arabic; 33% were Christians and 19% were Muslims. An increasing number of cases of nutritional rickets have been noted since 2000. Seventy-nine percent of patients with nutritional rickets presented at the emergency department, and in 69% of the cases, rickets was an incidental finding; 96% of patients were exclusively breast-fed, and none received multivitamin supplements. 25-OH vitamin D levels were below 5 ng/mL in 42% of the patients, all of whom were African Americans. We could document complete resolution of nutritional rickets in only 8 patients, and 3 of these patients showed sequelae of rickets.

MeSH terms

  • Breast Feeding / adverse effects
  • Child
  • Child, Preschool
  • Dietary Supplements
  • Female
  • Hospitals, Pediatric / statistics & numerical data*
  • Humans
  • Hydroxycholecalciferols / blood
  • Infant
  • Male
  • Michigan / epidemiology
  • Patients / statistics & numerical data
  • Rickets / drug therapy
  • Rickets / epidemiology
  • Rickets / etiology*
  • Vitamin D / administration & dosage
  • Vitamin D / therapeutic use
  • Vitamin D Deficiency / complications*
  • Vitamins / administration & dosage
  • Vitamins / therapeutic use

Substances

  • Hydroxycholecalciferols
  • Vitamins
  • Vitamin D