Musculoskeletal complications of neuromuscular disease in children

Phys Med Rehabil Clin N Am. 2008 Feb;19(1):163-94, viii. doi: 10.1016/j.pmr.2007.10.003.


A wide variety of neuromuscular diseases affect children, including central nervous system disorders such as cerebral palsy and spinal cord injury; motor neuron disorders such as spinal muscular atrophy; peripheral nerve disorders such as Charcot-Marie-Tooth disease; neuromuscular junction disorders such as congenital myasthenia gravis; and muscle fiber disorders such as Duchenne's muscular dystrophy. Although the origins and clinical syndromes vary significantly, outcomes related to musculoskeletal complications are often shared. The most frequently encountered musculoskeletal complications of neuromuscular disorders in children are scoliosis, bony rotational deformities, and hip dysplasia. Management is often challenging to those who work with children who have neuromuscular disorders.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Child
  • Female
  • Hip Dislocation, Congenital / diagnostic imaging
  • Hip Dislocation, Congenital / epidemiology
  • Hip Dislocation, Congenital / surgery*
  • Humans
  • Male
  • Musculoskeletal Diseases* / etiology
  • Musculoskeletal Diseases* / physiopathology
  • Musculoskeletal Diseases* / therapy
  • Neuromuscular Diseases / complications*
  • Radiography
  • Risk Factors
  • Scoliosis* / classification
  • Scoliosis* / diagnostic imaging
  • Scoliosis* / surgery