Nestin in central nervous system cells

Neurosci Behav Physiol. 2008 Feb;38(2):165-9. doi: 10.1007/s11055-008-0025-z.

Abstract

This literature review reflects current knowledge on the intermediate filament protein nestin, which most authors regard as a marker of "neural stem/progenitor cells." The structural-functional characteristics of nestin and its presence in various central nervous system cells at different stages of ontogenesis in normal and pathological conditions are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biomarkers
  • Cell Differentiation / physiology
  • Central Nervous System / cytology
  • Central Nervous System / metabolism
  • Central Nervous System / physiology*
  • Central Nervous System Diseases / metabolism
  • Central Nervous System Diseases / pathology
  • Female
  • Humans
  • Intermediate Filament Proteins / metabolism
  • Intermediate Filament Proteins / physiology*
  • Mice
  • Nerve Tissue Proteins / metabolism
  • Nerve Tissue Proteins / physiology*
  • Nestin
  • Neurons / metabolism
  • Neurons / physiology
  • Pregnancy
  • Spinal Cord Injuries / metabolism
  • Spinal Cord Injuries / pathology

Substances

  • Biomarkers
  • Intermediate Filament Proteins
  • NES protein, human
  • Nerve Tissue Proteins
  • Nes protein, mouse
  • Nestin