Interpreting fMRI data: maps, modules and dimensions

Nat Rev Neurosci. 2008 Feb;9(2):123-35. doi: 10.1038/nrn2314.

Abstract

Neuroimaging research over the past decade has revealed a detailed picture of the functional organization of the human brain. Here we focus on two fundamental questions that are raised by the detailed mapping of sensory and cognitive functions and illustrate these questions with findings from the object-vision pathway. First, are functionally specific regions that are located close together best understood as distinct cortical modules or as parts of a larger-scale cortical map? Second, what functional properties define each cortical map or module? We propose a model in which overlapping continuous maps of simple features give rise to discrete modules that are selective for complex stimuli.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain Mapping / methods*
  • Cerebral Cortex / anatomy & histology*
  • Cerebral Cortex / physiology*
  • Cognition / physiology
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Magnetic Resonance Imaging / methods*
  • Nerve Net / anatomy & histology*
  • Nerve Net / physiology*
  • Sensation / physiology
  • Visual Cortex / physiology
  • Visual Perception / physiology