Navigating through models of chemotaxis

Curr Opin Cell Biol. 2008 Feb;20(1):35-40. doi: 10.1016/ Epub 2008 Jan 18.


Chemotaxis in eukaryotic cells involves the coordination of several related but separable processes: motility, polarization, and gradient sensing. Mathematical models that have been proposed to explain chemotaxis typically focus on only one of these processes. We summarize the strengths and weaknesses of the models and point out the need for an integrated model.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Cell Polarity
  • Chemotaxis*
  • Models, Biological*