[Effects of Epimedium sagittatum Maxim. Polysaccharides on DNA synthesis of bone marrow cells of "yang deficiency" animal model caused by hydroxyurea]

Zhongguo Zhong Yao Za Zhi. 1991 Oct;16(10):620-2, inside back cover.
[Article in Chinese]

Abstract

A study was made on the effects of Epimedium sagittatum polysaccharides on DNA synthesis of bone marrow cells of "yang deficiency" animal model caused by hydroxyurea with methods of cell culture in vitro and determination of 3H-TdR incorporating DNA of bone marrow cells. The results showed that after the treatment with 100 micrograms of Epimedium sagittatum polysaccharides, the cell multiplication rate was increased by 72% and DNA synthesis rate increased by 68%, in 1 x 10(6) cells.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Bone Marrow / drug effects*
  • Bone Marrow Cells
  • Cell Division / drug effects
  • DNA / biosynthesis*
  • Medicine, Chinese Traditional
  • Mice
  • Plants, Medicinal* / chemistry
  • Polysaccharides / pharmacology*
  • Yang Deficiency / pathology*

Substances

  • Polysaccharides
  • DNA