Treatment of limb apraxia: moving forward to improved action

Am J Phys Med Rehabil. 2008 Feb;87(2):149-61. doi: 10.1097/PHM.0b013e31815e6727.


Limb apraxia is a common disorder of skilled, purposive movement that is frequently associated with stroke and degenerative diseases such as Alzheimer disease. Despite evidence that several types of limb apraxia significantly impact functional abilities, surprisingly few studies have focused on development of treatment paradigms. Additionally, although the most disabling types of apraxia reflect damage to gesture and/or object memory systems, existing treatments have not fully taken advantage of principles of experience known to affect learning and neural plasticity. We review the current state of the art in the rehabilitation of limb apraxia, indicate possible points of contact with the learning literature, and generate suggestions for how translational principles might be applied to the development of future research on treatment of this disabling disorder.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Apraxia, Ideomotor / drug therapy
  • Apraxia, Ideomotor / physiopathology*
  • Apraxia, Ideomotor / rehabilitation
  • Apraxias / drug therapy
  • Apraxias / physiopathology
  • Apraxias / rehabilitation
  • Cognition
  • Cognition Disorders
  • Disease Progression
  • Humans
  • Neuronal Plasticity
  • Treatment Outcome