Abstract
Thyrotropin-releasing factor was given orally to 12 impotent patients in a dose of 43 mg daily for 4 weeks in a double-blind crossover technique and compared with placebo. TRF showed no beneficial effect over placebo. In these patients, thyroid function and the hypothalamic-pituitary-thyroid axis were examined by measuring T3, T4, and TSH before and after the TRF test. There were no pathological findings for patients included in this study.
Publication types
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Clinical Trial
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Controlled Clinical Trial
MeSH terms
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Adult
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Clinical Trials as Topic
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Erectile Dysfunction / blood
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Erectile Dysfunction / drug therapy
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Erectile Dysfunction / physiopathology*
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Humans
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Hypothalamo-Hypophyseal System / drug effects
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Hypothalamo-Hypophyseal System / physiopathology*
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Male
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Middle Aged
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Spermatogenesis
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Synaptic Transmission / drug effects
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Testosterone / blood
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Thyroid Function Tests
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Thyroid Gland / drug effects
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Thyroid Gland / physiopathology*
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Thyroid Hormones / blood
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Thyrotropin / blood
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Thyrotropin-Releasing Hormone / administration & dosage
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Thyrotropin-Releasing Hormone / therapeutic use
Substances
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Thyroid Hormones
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Testosterone
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Thyrotropin-Releasing Hormone
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Thyrotropin