Abstract
Citalopram is a very potent and highly selective inhibitor of neuronal serotonin (5-hydroxytryptamine, or 5-HT). Serotonin syndrome is a rarely observed side-effect of Citalopram use. This report discusses a case of first time, low dose citalopram use-related serotonin syndrome presenting with confusion, hyperhidrosis, hyperreflexia, myoclonus and fever.
MeSH terms
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Adult
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Antidepressive Agents, Second-Generation / administration & dosage
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Antidepressive Agents, Second-Generation / adverse effects*
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Citalopram / administration & dosage
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Citalopram / adverse effects*
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Confusion / chemically induced
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Cyproheptadine / therapeutic use
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Fever / chemically induced
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Fluid Therapy
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Humans
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Hyperhidrosis / chemically induced
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Male
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Myoclonus / chemically induced
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Reflex, Abnormal / drug effects
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Selective Serotonin Reuptake Inhibitors / administration & dosage
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Selective Serotonin Reuptake Inhibitors / adverse effects*
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Serotonin Antagonists / therapeutic use
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Serotonin Syndrome / chemically induced*
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Serotonin Syndrome / therapy
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Treatment Outcome
Substances
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Antidepressive Agents, Second-Generation
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Serotonin Antagonists
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Serotonin Uptake Inhibitors
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Citalopram
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Cyproheptadine