In this work the evolution of diabetic preretinopathy after a 1.5 year follow-up period among 30 insulin dependent and non-insulin dependent adult-onset diabetics with short duration of diabetes is examined. Ophthalmoscopy and intravenous fluorescein angiography were the methods of examination. Diabetic pre-retinopathy progressed into diabetic retinopathy in 36.7% of the cases, remained stationary in 43.3%, and regressed in 20.0% of the cases. This study shows the need for frequent ophthalmoscopic controls of diabetics because of the importance of early treatment of diabetic retinopathy.