Changes in the DZ unlike/like sex ratio in The Netherlands

Acta Genet Med Gemellol (Roma). 1991;40(3-4):319-23. doi: 10.1017/s0001566000003500.


Based on Dutch twin incidence figures since the beginning of the current century, evidence is provided in support of the idea that the DZ unlike/like sexed ratio has gradually shifted (since 1900) from unity to less than unity. Opposing conclusions with regard to the justification of the use of Weingberg's differential rule are very probably correct in themselves but could depend on country and period of birth of the twin sample used. Furthermore, the fast drop and subsequent rise in DZ twinning rate between about 1963 and 1990 can very likely for the greater part be ascribed to a parallel shift in maternal age.

MeSH terms

  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Maternal Age
  • Netherlands / epidemiology
  • Pregnancy
  • Pregnancy, Multiple
  • Sex Ratio*
  • Twins, Dizygotic / statistics & numerical data*
  • Twins, Monozygotic / statistics & numerical data