Minimizing adverse drug events in older patients

Am Fam Physician. 2007 Dec 15;76(12):1837-44.


Adverse drug events are common in older patients, particularly in those taking at least five medications, but such events are predictable and often preventable. A rational approach to prescribing in older adults integrates physiologic changes of aging with knowledge of pharmacology. Focusing on specific outcomes, such as the prompt recognition of adverse drug events, allows the family physician to approach prescribing cautiously and confidently. Physicians need to find ways to streamline the medical regimen, such as periodically reviewing all medications in relation to the Beers criteria and avoiding new prescriptions to counteract adverse drug reactions. The incorporation of computerized alerts and a multidisciplinary approach can reduce adverse drug events.

Publication types

  • Review

MeSH terms

  • Aged
  • Drug Information Services / standards
  • Drug Prescriptions / standards*
  • Drug Therapy, Computer-Assisted / methods
  • Drug Utilization / standards
  • Humans
  • Medication Errors / prevention & control*
  • Primary Health Care / standards*
  • Risk Assessment