Comparative phylogenomic analyses of teleost fish Hox gene clusters: lessons from the cichlid fish Astatotilapia burtoni: comment

BMC Genomics. 2008 Jan 24;9:35. doi: 10.1186/1471-2164-9-35.


A reanalysis of the sequences reported by Hoegg et al has highlighted the presence of a putative HoxC1a gene in Astatotilapia burtoni. We discuss the evolutionary history of the HoxC1a gene in the teleost fish lineages and suggest that HoxC1a gene was lost twice independently in the Neoteleosts. This comment points out that combining several gene-finding methods and a Hox-dedicated program can improve the identification of Hox genes.

Publication types

  • Comment
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bayes Theorem
  • Cichlids / classification
  • Cichlids / genetics*
  • Evolution, Molecular
  • Genes, Homeobox*
  • Genome*
  • Multigene Family*
  • Phylogeny*
  • Pseudogenes