Zinc supplementation for the treatment or prevention of disease: current status and future perspectives

Exp Gerontol. 2008 May;43(5):394-408. doi: 10.1016/j.exger.2007.12.002. Epub 2007 Dec 14.


Zinc is a nutritionally essential trace element, and thus zinc deficiency may severely affect human health. Many studies were published in which the effect of nutritional zinc supplementation on the incidence or severity of a certain disease was investigated. This review summarizes the main observations and aims to evaluate the use of nutritional zinc supplementation for prevention and treatment of human disease.

Publication types

  • Review

MeSH terms

  • Arthritis / diet therapy
  • Diabetes Mellitus / diet therapy
  • Diarrhea / prevention & control
  • Dietary Supplements
  • Genetic Diseases, Inborn / diet therapy
  • Humans
  • Immune System Diseases / diet therapy
  • Infections / diet therapy
  • Skin Diseases / diet therapy
  • Trace Elements / administration & dosage*
  • Vaccination
  • Zinc / administration & dosage*
  • Zinc / deficiency


  • Trace Elements
  • Zinc