Ictal SPECT in Sturge-Weber syndrome

Epilepsy Res. 2008 Feb;78(2-3):240-3. doi: 10.1016/j.eplepsyres.2007.12.006. Epub 2008 Jan 25.


We report on a patient with right-sided Sturge-Weber syndrome (SWS), in whom earlier functional hemispherectomy failed. Subtraction of ictal and interictal single-photon-emission-computed-tomography (SPECT) superimposed on individual MRI showed a right fronto-orbital hyperperfusion, with a left-sided EEG seizure pattern. Ictal SPECT supported our assumption that right frontal originated seizure pattern propagated to left hemisphere via the remaining right frontal bridge. Right orbito-frontal resection and disconnection from corpus callosum resulted in seizure freedom.

Publication types

  • Case Reports

MeSH terms

  • Anticonvulsants / therapeutic use
  • Child
  • Corpus Callosum / surgery
  • Drug Resistance
  • Electroencephalography
  • Frontal Lobe / surgery
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Male
  • Neurosurgical Procedures
  • Paresis / etiology
  • Seizures / diagnostic imaging*
  • Seizures / etiology
  • Sturge-Weber Syndrome / complications
  • Sturge-Weber Syndrome / diagnostic imaging*
  • Tomography, Emission-Computed, Single-Photon


  • Anticonvulsants