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, 90 (4), 1290-3

Transient Receptor Potential Vanilloid receptor-1 Confers Heat Resistance to Male Germ Cells

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Transient Receptor Potential Vanilloid receptor-1 Confers Heat Resistance to Male Germ Cells

Sefika Canan Mizrak et al. Fertil Steril.

Abstract

Testicular hyperthermia in mice lacking transient receptor potential vanilloid receptor-1 results in a much more rapid and massive germ cell depletion from the seminiferous tubules than in wild-type animals, indicating that this receptor protects germ cells against heat stress.

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