Early determinative events in Caenorhabditis elegans

Curr Opin Genet Dev. 1991 Aug;1(2):179-84. doi: 10.1016/s0959-437x(05)80067-x.


Classical developmental biology has distinguished two major modes of embryogenesis, determinate and indeterminate. Nematodes have been considered the chief paradigm for determinate and cell-autonomous development, but recent experiments on the early development of Caenorhabditis elegans suggest that most blastomeres of this nematode are, in fact, determined by interactions.

Publication types

  • Review

MeSH terms

  • Animals
  • Blastocyst
  • Caenorhabditis / embryology*
  • Caenorhabditis / genetics
  • Cell Communication
  • Genes, Lethal
  • Morphogenesis
  • Mosaicism
  • Mutation