Loss of vision associated with angioid streaks in beta-thalassemia intermedia

Int J Hematol. 2008 Jan;87(1):35-8. doi: 10.1007/s12185-007-0014-y. Epub 2007 Dec 11.


An acquired diffuse elastic tissue defect that resembles inherited pseudoxanthoma elasticum (PXE) has been noticed with a significant age-related frequency in hemoglobin disorders, especially beta-thalassemia and has been held responsible for a number of complications observed in these cases, some of which are quite severe. We report here two patients with beta-thalassemia intermedia, who presented with severe visual acuity impairment associated with angioid streaks, the typical ocular manifestation of PXE.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angioid Streaks / etiology*
  • Angioid Streaks / pathology
  • Blindness / etiology*
  • Blindness / pathology
  • Female
  • Humans
  • Male
  • Middle Aged
  • beta-Thalassemia / complications*