Obscure gastrointestinal bleeding: evaluation with 64-section multiphase CT enterography--initial experience

Radiology. 2008 Feb;246(2):562-71. doi: 10.1148/radiol.2462061920.


This retrospective HIPAA-compliant study was approved by the institutional review board and institutional conflict of interest committee. Patients gave informed consent for use of medical records. The purpose of the study was to retrospectively evaluate the findings depicted at computed tomographic (CT) enterography performed with a 64-section CT system and by using neutral enteric contrast material and a three-phase acquisition in patients with obscure gastrointestinal bleeding (OGIB). Twenty-two outpatients (11 men, 11 women; age range, 37-83 years) with OGIB underwent CT enterography. Findings were compared with capsule and traditional endoscopic, surgical, and angiographic findings. CT enterographic findings were positive for a bleeding source in 10 (45%) of 22 patients. Eight of 10 positive findings at CT enterography were also positive at capsule endoscopy or subsequent clinical diagnosis. CT enterography helped correctly identify three lesions undetected at capsule endoscopy. Study results suggest that multiphase, multiplanar CT enterography may have a role in the evaluation of OGIB.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Gastrointestinal Hemorrhage / diagnostic imaging*
  • Gastrointestinal Tract / diagnostic imaging*
  • Humans
  • Male
  • Middle Aged
  • Pilot Projects
  • Radiographic Image Enhancement / methods
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / instrumentation
  • Tomography, X-Ray Computed / methods*