Successful conservative treatment of endocervical adenocarcinoma stage Ib1 diagnosed early in pregnancy

Acta Obstet Gynecol Scand. 2008;87(2):250-3. doi: 10.1080/00016340701870794.


Traditionally when cervical cancer is diagnosed during the first trimester of pregnancy, oncological treatment is given priority despite the pregnant state. A 32-year-old primigravida was diagnosed with invasive endocervical adenocarcinoma stage Ib1 at 8 weeks' gestation. As the patient wanted to preserve the pregnancy, an amputation of the anterior cervix and retroperitoneal pelvic lymphadenectomy were performed. Based on favourable prognostic markers, we decided to maintain the pregnancy with careful cytological and histological follow-up. The patient gave birth at term to a healthy boy, and 18 months after the delivery there is no evidence of recurrent disease. In the absence of poor prognostic markers, we decided to adopt a conservative approach for cervical adenocarcinoma in a pregnant patient at 8 weeks' gestation.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / surgery*
  • Adult
  • Cervix Uteri / surgery
  • Early Diagnosis*
  • Female
  • Humans
  • Lymph Node Excision
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnosis
  • Pregnancy Complications, Neoplastic / surgery*
  • Pregnancy Trimester, First
  • Uterine Cervical Neoplasms / diagnosis
  • Uterine Cervical Neoplasms / surgery*