Calcium intake and metabolic bone disease after eight years of Roux-en-Y gastric bypass

Obes Surg. 2008 Apr;18(4):386-90. doi: 10.1007/s11695-007-9393-7. Epub 2008 Jan 31.


Background: Roux-en-Y gastric bypass (RYGBP) has been found to be the most efficient way to lose weight and maintain the weight loss in morbid obesity. However, with the formation of a new stomach and the modification of intestinal anatomy, there are significant changes on physiological properties of these organs that lead to nutrient deficiency, including calcium. The objectives of this study were to evaluate calcium intake, bone metabolism, and prevalence of metabolic bone disease in women subjected to RYGBP after 8 years.

Methods: Food frequency questionnaire and 3-day dietary recall, laboratory tests of bone metabolism and bone mineral density were accessed.

Results: Calcium intake was below the recommendation in all women. Serum PTH and alkaline phosphatase were elevated, whereas vitamin D and urinary calcium were significantly lower. Also, a higher prevalence of metabolic bone disease than the one expected for the normal population at the same age was noted.

Conclusion: These data suggest that metabolic bone disease could be a complication of this type of surgery.

MeSH terms

  • Adult
  • Aged
  • Bone Diseases, Metabolic / epidemiology*
  • Bone Remodeling / physiology*
  • Calcium, Dietary*
  • Diet*
  • Female
  • Follow-Up Studies
  • Gastric Bypass*
  • Humans
  • Middle Aged
  • Nutritional Status
  • Obesity, Morbid / complications
  • Obesity, Morbid / metabolism*
  • Obesity, Morbid / surgery
  • Patient Compliance
  • Time Factors


  • Calcium, Dietary