Immunology. The toll of cathepsin K deficiency

Science. 2008 Feb 1;319(5863):576-7. doi: 10.1126/science.1154207.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Autoimmune Diseases / immunology*
  • Autoimmune Diseases / metabolism
  • Cathepsin K
  • Cathepsins / antagonists & inhibitors
  • Cathepsins / deficiency
  • Cathepsins / metabolism*
  • Cytokines / metabolism
  • DNA, Bacterial / metabolism
  • DNA, Viral / metabolism
  • Dendritic Cells / immunology
  • Dinucleoside Phosphates / immunology
  • Dinucleoside Phosphates / metabolism
  • Endoplasmic Reticulum / metabolism
  • Endosomes / metabolism
  • Humans
  • Immunity, Innate*
  • Inflammation / immunology*
  • Inflammation / metabolism
  • Lysosomes / metabolism
  • Mice
  • Protease Inhibitors / pharmacology
  • Rats
  • Signal Transduction
  • Toll-Like Receptor 9 / antagonists & inhibitors
  • Toll-Like Receptor 9 / metabolism*

Substances

  • Cytokines
  • DNA, Bacterial
  • DNA, Viral
  • Dinucleoside Phosphates
  • Protease Inhibitors
  • Toll-Like Receptor 9
  • cytidylyl-3'-5'-guanosine
  • Cathepsins
  • CTSK protein, human
  • Cathepsin K
  • Ctsk protein, mouse
  • Ctsk protein, rat