Abstract
Hepatoprotective activity of pyrimidine derivative hydroxymethyluracil was studied on the model of acute paracetamol-induced liver damage in rats. Hydroxymethyluracil was shown to produce a strong hepatoprotective effect.
MeSH terms
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Acetaminophen / toxicity*
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Alanine Transaminase / blood
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Animals
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Aspartate Aminotransferases / blood
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Liver / drug effects*
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Male
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Pentoxyl / analogs & derivatives*
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Pentoxyl / pharmacology
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Rats
Substances
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Acetaminophen
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5-hydroxymethyluracil
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Pentoxyl
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Aspartate Aminotransferases
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Alanine Transaminase