Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
, 108 (2), 292-8

Effect of Spinal Cord Stimulation for Chronic Complex Regional Pain Syndrome Type I: Five-Year Final Follow-Up of Patients in a Randomized Controlled Trial

Affiliations
Randomized Controlled Trial

Effect of Spinal Cord Stimulation for Chronic Complex Regional Pain Syndrome Type I: Five-Year Final Follow-Up of Patients in a Randomized Controlled Trial

Marius A Kemler et al. J Neurosurg.

Abstract

Object: Chronic complex regional pain syndrome-Type I (CRPS-I) is a painful, disabling disorder for which no treatment with proven effect is available. In the present randomized controlled trial, the authors assessed the effectiveness of spinal cord stimulation (SCS) in reducing pain due to CRPS-I at the 5-year follow-up.

Methods: The authors performed a randomized trial in a 2:1 ratio in which 36 patients with CRPS-I were allocated to receive SCS and physical therapy (PT) and 18 patients to receive PT alone. Twenty-four patients who received SCS+PT also underwent placement of a permanent spinal cord stimulator after successful test stimulation; the remaining 12 patients did not receive a permanent stimulator. The authors assessed pain intensity, global perceived effect, treatment satisfaction, and health-related quality of life. Patients were examined before randomization, before implantation, and every year until 5 years thereafter. Ten patients were excluded from the final analysis.

Results: At 5 years posttreatment, SCS+PT produced results similar to those following PT for pain relief and all other measured variables. In a subgroup analysis, the results with regard to global perceived effect (p=0.02) and pain relief (p=0.06) in 20 patients with an implant exceeded those in 13 patients who received PT.

Conclusions: Despite the diminishing effectiveness of SCS over time, 95% of patients with an implant would repeat the treatment for the same result.

Similar articles

See all similar articles

Cited by 39 PubMed Central articles

See all "Cited by" articles

Publication types

MeSH terms

LinkOut - more resources

Feedback