Medication, allergy, and adverse drug event discrepancies in ambulatory care

Fam Med. 2008 Feb;40(2):107-10.

Abstract

Background and objectives: A first step in reducing medication errors is for health care workers to be aware of a patient's medications, allergies, and any previously documented adverse drug events (ADEs). This study sought to determine the frequency of medication and allergy/ADE-related discrepancies in a family medicine residency clinic.

Methods: Patients were contacted prior to appointments and asked to bring in prescription and over-the-counter medications. A research assistant interviewed 157 patients and recorded each drug a patient was taking, together with dosage, dosing frequency, known allergies, and demographic information. This information was then compared to similar information in the medical record.

Results: Overall, 97% of patients had at least one discrepancy between medications listed in the medical record and medications they were taking, and 32% had an allergy/ADE discrepancy. Discrepancies were highest for women, those with cardiovascular disease, and those hospitalized within the last year. Only the total number of medications was predictive of a discrepancy, however, accounting for 25% of the variability.

Conclusions: A higher medication discrepancy rate existed in this family medicine residency clinic than the 26%--76% rate that is documented in the literature. The results point to a need for better medication, allergy, and ADE awareness.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Ambulatory Care / organization & administration*
  • Continuity of Patient Care / organization & administration
  • Drug Hypersensitivity*
  • Drug Utilization
  • Drug-Related Side Effects and Adverse Reactions*
  • Family Practice / organization & administration
  • Female
  • Humans
  • Male
  • Medical History Taking*
  • Medication Errors*
  • Middle Aged
  • Socioeconomic Factors