Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2008 Jun;12(6):1015-21.
doi: 10.1007/s11605-008-0484-0. Epub 2008 Feb 7.

Is Totally Laparoscopic Gastrectomy Less Invasive Than Laparoscopy-Assisted Gastrectomy?: Prospective, Multicenter Study

Affiliations
Clinical Trial

Is Totally Laparoscopic Gastrectomy Less Invasive Than Laparoscopy-Assisted Gastrectomy?: Prospective, Multicenter Study

Kyo Young Song et al. J Gastrointest Surg. .

Abstract

Background: Laparoscopic surgery has been adopted for the treatment of gastric cancer, and many reports have confirmed its favorable outcomes. Most surgeons prefer to laparoscopy-assisted gastrectomy using minilaparotomy rather than totally laparoscopic procedures because of technical difficulties of intracorporeal anastomosis. We conducted this study to compare laparoscopy-assisted distal gastrectomy with totally laparoscopic distal gastrectomy. In addition, laparoscopic procedures were compared with open distal gastrectomy.

Material and methods: This prospective, nonrandomized, multicenter study enrolled 60 patients with early gastric cancer at three branch hospitals of our institutes. Twenty-five- to 30-cm-long mid-line incision, 5-cm midline or transverse incision, and 3-cm U-shaped incision were used in open distal gastrectomy, laparoscopy-assisted distal gastrectomy, and totally laparoscopic distal gastrectomy, respectively. Postoperative outcomes, immunologic changes, and operation-related costs were compared between the three groups.

Results: There was no difference in gender, mean age, body mass index, and tumor characteristics between the three groups. No operation-related death occurred. Estimated blood loss, number of additional analgesics use, first flatus, and soft meal diet time were significantly different between the three groups (P < 0.05). In totally laparoscopic distal gastrectomy, the time to first flatus was significantly shorter than laparoscopy-assisted distal gastrectomy (3.7 vs. 2.8 days, in laparoscopy-assisted distal gastrectomy and totally laparoscopic distal gastrectomy, respectively, P < 0.05). White blood cell count and C-reactive protein level at postoperative day 1 were significantly higher in open distal gastrectomy than the other groups; however, there was no difference between laparoscopy-assisted distal gastrectomy and totally laparoscopic distal gastrectomy. The operation-related costs were significantly greater in totally laparoscopic distal gastrectomy (P < 0.05).

Conclusion: Although totally laparoscopic distal gastrectomy needs more cost, totally laparoscopic distal gastrectomy provides shorter bowel recovery time than laparoscopy-assisted distal gastrectomy.

Similar articles

See all similar articles

Cited by 78 articles

See all "Cited by" articles

References

    1. Eur J Gastroenterol Hepatol. 2006 Aug;18(8):855-61 - PubMed
    1. Surg Endosc. 2008 Mar;22(3):655-9 - PubMed
    1. Gastric Cancer. 1999 Nov;2(3):186-190 - PubMed
    1. J Am Coll Surg. 2005 Feb;200(2):191-7 - PubMed
    1. J Am Coll Surg. 2003 Jan;196(1):75-81 - PubMed

LinkOut - more resources

Feedback