Possible impact of the NHK special questioning cancer treatment in Japan on clinicians' prescriptions of oxaliplatin

Jpn J Clin Oncol. 2008 Jan;38(1):78-83. doi: 10.1093/jjco/hym148.


Medical information through media may influence physicians' prescriptions of medication. The Japan Broadcasting Corporation (NHK) aired on April and May 2005, a special program called 'Questioning Cancer Treatment in Japan', covering oxaliplatin. We investigated potential impact of this program on prescriptions, utilizing a post-marketing clinical trial monitoring of all patients receiving oxaliplatin. The post-marketing clinical trial reached the target sample size of 1200 by the 4th week of May, 44 weeks sooner than anticipated. The newly registered numbers of facilities and patients exhibited a bimodal peak in April and June. The viewer rating of NHK special was 8.3%, whereas three national newspapers and one weekly magazine took up the minor articles of oxaliplatin. In July 2007, 405 clinicians sent a written opinion to NHK, stating 'NHK special invites misperceptions and confusions to public.' NHK special might have had an impact on clinicians' prescriptions of oxaliplatin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Communication
  • Decision Making*
  • Humans
  • Japan
  • Mass Media*
  • Medical Oncology
  • Neoplasms / drug therapy*
  • Newspapers as Topic
  • Organoplatinum Compounds / therapeutic use*
  • Oxaliplatin


  • Antineoplastic Agents
  • Organoplatinum Compounds
  • Oxaliplatin