Simvastatin treatment shows no effect on the incidence of cerebral malaria or parasitemia during experimental malaria

Antimicrob Agents Chemother. 2008 Apr;52(4):1583-4. doi: 10.1128/AAC.01428-07. Epub 2008 Feb 11.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Animals
  • Disease Models, Animal*
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
  • Incidence
  • Malaria, Cerebral / drug therapy*
  • Malaria, Cerebral / epidemiology*
  • Malaria, Cerebral / parasitology
  • Mice
  • Mice, Inbred C57BL
  • Parasitemia / drug therapy*
  • Parasitemia / epidemiology*
  • Parasitemia / parasitology
  • Plasmodium berghei / drug effects*
  • Plasmodium falciparum
  • Simvastatin / administration & dosage
  • Simvastatin / therapeutic use*
  • Treatment Outcome

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Simvastatin