Abstract
The DSM-III-R diagnoses of a group of adoptees were predicted by the MMPI (Minnesota Multiphasic Personality Inventory) schizophrenia-related scales in the Finnish Adoptive Family Study. The sample consisted of 60 high-risk (HR) adopted-away offspring of biologic mothers with a diagnosis of broad schizophrenia spectrum and 76 low-risk (LR) control adoptees. They were assessed with the MMPI before the onset of any psychiatric disorder at a mean age of 24 years. High scores on the Psychopathic Deviate scale predicted psychiatric disorder at 11-year follow-up. Furthermore, LR adoptees', but not HR adoptees', mental disorders could be predicted with the MMPI scales Psychopathic Deviate and Golden-Meehl Indicators. These scales measure schizophrenia-related personality traits, including a social behavior, anhedonia, ambivalence, interpersonal aversiveness, and formal thought disturbances.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adoption / psychology*
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Adult
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Affective Symptoms / diagnosis
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Affective Symptoms / epidemiology
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Age Factors
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Child
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Child of Impaired Parents / psychology*
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Child of Impaired Parents / statistics & numerical data
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Diagnostic and Statistical Manual of Mental Disorders
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Female
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Finland / epidemiology
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Follow-Up Studies
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Genetic Predisposition to Disease / epidemiology
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Genetic Predisposition to Disease / psychology
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Humans
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Interpersonal Relations
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Longitudinal Studies
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MMPI / statistics & numerical data*
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Male
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Mental Disorders / diagnosis*
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Mental Disorders / epidemiology
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Mental Disorders / genetics
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Personality Assessment
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Predictive Value of Tests
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Psychiatric Status Rating Scales / statistics & numerical data
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Risk Factors
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Schizophrenia / diagnosis
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Schizophrenia / epidemiology*
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Schizophrenia / genetics
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Schizophrenic Psychology*
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Social Behavior
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Social Class