Abstract
Fifty-six Newcastle disease virus strains collected from 2000 to 2006 could be grouped into subgenotype VIId. However, they displayed cumulative mutations in and around the linear epitope of hemagglutinin-neuraminidase (residues 345 to 353) with time. The antigenicities of the variants that became predominant in Korea differ from each other and from the wild type.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Antigenic Variation*
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Chickens / virology
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Epitopes / chemistry
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Epitopes / genetics*
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Epitopes / immunology
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Genetic Variation*
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HN Protein / chemistry
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HN Protein / genetics*
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HN Protein / immunology
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Models, Molecular
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Molecular Sequence Data
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Mutation
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Newcastle Disease / virology
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Newcastle disease virus / genetics
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Newcastle disease virus / immunology*
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Peptides / chemical synthesis
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Peptides / chemistry
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Peptides / immunology
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Poultry Diseases / virology
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Sequence Analysis, DNA
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Viral Fusion Proteins / chemistry
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Viral Fusion Proteins / genetics
Substances
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Epitopes
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HN Protein
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Peptides
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Viral Fusion Proteins