A new pd-catalyzed cascade reaction for the synthesis of strained aromatic polycycles

Gaëlle Blond; Christophe Bour; Bahaâ Salem; Jean Suffert

doi:10.1021/ol702855h

A new pd-catalyzed cascade reaction for the synthesis of strained aromatic polycycles

Org Lett. 2008 Mar 20;10(6):1075-8. doi: 10.1021/ol702855h. Epub 2008 Feb 15.

Authors

Gaëlle Blond¹, Christophe Bour, Bahaâ Salem, Jean Suffert

Affiliation

¹ Université Louis Pasteur de Strasbourg (LC01 UMR 7175 CNRS/ULP), Faculté de Pharmacie, 74 route du Rhin, Illkirch-Cedex, France.

PMID: 18275204
DOI: 10.1021/ol702855h

Abstract

Two new palladium catalyzed cascade reactions involving a 4-exo-dig cyclocarbopalladation are described. These processes are shown to convert bromoenediynes and bromodienynes into strained aromatic compounds in a single step.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Magnetic Resonance Spectroscopy
Palladium / chemistry*
Polycyclic Compounds / chemistry*

Substances

Polycyclic Compounds
Palladium